Objective: Adolescence is a very important period of human’s life in terms of social and cultural development including emotional lability and psychosocial maturation in parallel with rapid biological changes. During this period the risky behaviors such as frequent smoking, alcohol, drugs, truancy, violence and status fault are extremly important for adolescent health and future. In this study we aimed to investigate the influencing factors, frequency and distribution of risky behaviors in adolescents aged 11 to 19 who were studying in schools in Ankara. Methods: This cross-sectional study was applied on the adolescents who between the ages of 11-19, a total of 2756 students in the seven types of schools in May and June of 2014 in the center of Ankara. The trends of adolescent’s risky behaviors were evaluated using İllegal Behavior Scale that was developed by Kaner. Results: Total İllegal Behavior Scale of all students in the study was determined as average point 53.95 and as median point 49. All the factors other than the type of school, on the total İllegal Behavior Scale scores were found as statistically significant effect. The most effective first three factors were determined as the status of student’s smoking, the status of drug-using friends, the average of rationing grade point (respectively; p <0.001, p <0.001, p <0.001). Male gender was more effective on the all risky behaviors other than copy and this difference between the sexes was statistically significant (p <0.001). The risky behavior which highest mean and median value was found as status crime-to behave of against rules of the school. Total İllegal Behavior Scale scores were determined as lowest scores in the students of the Arts-Fitness Schools and the Imam-Preacher Schools (p <0.001). Conclusion: As the our study, the determination of risky behaviors of adolescents and the influencing factors of risky behaviours may contribute for new methods of training and measures.

Objective: To investigate homocysteine and related factors in Type 2 Diabetes Mellitus patients taking oral antidiabetic medication. Material-Method: The study included type 2 diabetic patients who were taking oral antidiabetic medication and presented to Diabetes and Family Medicine outpatient clinic of MoH Ankara Training and Research Hospital in Sept. 2008 and Jan. 2009. Demographic and clinical data of patients were recorded. Weight, height, waist circumference were measured and body mass index (BMIs) were calculated. Glucose, urea, creatinine, uric acid, ALT, AST, lipid profiles, sodium, potassium, HbA1c, homocysteine, insulin, vitamin B-12, folic acid and urinary microalbumin were measured. HOMA-IR values were calculated. Results: The mean age of patients was 50.1±9.5; 32.7% (n=18) was men and 67.3% (n=37) was women. While there was no significant difference between homocysteine and gender (p=0,162), menopausal state in women (p=0,103) and smoking (p=0,499); positive correlation between homocysteine and age, creatinine and uric acid, in women positive correlation between homocysteine and age, creatinine and uric acid, in premenopausal women positive correlation between homocysteine and age and negative correlation between homocysteine and ALT, in postmenopausal women positive correlation between homocysteine and age, BMI and uric acid were found. There was positive correlation between homocysteine and age and postprandial blood glucose in smokers. When set point of homocysteine was determined as 12 µmol/L, uric acid levels were close to be significantly higher in homocysteine ?12 µmol/L group (p=0.053). Conclusion: Homocysteine which is accepted as an independent risk factor for cardiovascular disease is seen important in diabetes which is especially a kind of cardiovascular disease itself. Considering the multiple factors that influence homocysteine, multi-center, large-scale, prospective studies are needed with correction of all factors.

Objective: Phenomenon of the fat talk is associated with negative body image, low self-esteem, body dissatisfaction, sociocultural pressures to be thin and cognitive distortions related with the body. In this study we aimed to investigate the effects of fat talk on depression, life satisfaction and body mass index. Methods: The study consisted of 107 women who participated. The data was collected survey and via internet between the dates of 21 December 2015 and 31 January 2016. Negative Body Talk Scale, Life Satisfaction Scale and Beck Depression Scale were used. Correlational methods, Student’s t test and Mann-Whitney U test were used to analyze the data. Data were analyzed by PASW 18 (SPSS/IBM, Chicago, IL, USA) programme. Results: The fat talks were often seen in overweight and obesed participants. The fat talk, was determined to have an effect on increasing the degree of depression. Positive correlation between body mass index (BMI) and the fat talk, body anxiety and body compaöring was found. The fat talk was not affected by factors such as marital status and age. There was no statistically significant relationship between life satisfaction and body anxiety, BMI and fat talks. Conclusion: The phenomenon of fat talk is required in order to consider the effects of the risk factors such as eating attitude, depression and BMI.

Abuse of products containing synthetic cannabinoids has become a recent concern. Advertised as “herbal incense”, these products are sold at smoke or head shops and over the internet under a variety of names such as “Spice, K2, Super Nova, Yucatan Fire, Diamond and Cloud 9”. Synthetic cannabinoids are functionally similar to tetrahydrocannabinol (THC) and mimic the effects of marijuana when smoked. However, many of them are stronger than THC and pose a greater health risk. Short-term loss of consciousness, paranoid hallucinations, pallor, tremors and seizures are common symptoms. At least of synthetic cannabinoids may have carsinogenic potential. The rapid growth in popularity of synthetic cannabinoid use among teens and adults is of serious in our country as all of the world. Some of these compounds were taken the list of prohibited substances in our country since 2010 according to the Early Warning System (EWS). They are preferred because of having an affordable price and no banning by law-enforcement. Formulations of these compound are new and rapidly evolving. For this reason, there is no a common mass or ultraviolet library of synthetic cannabinoids. It is difficult to detect and identify because they do not show cross-reactivity in drug test assays. In this study we aimed to present a general approach to synthetic cannabinoids.

Warfarin is an oral anticoagulant, can lead to skin necrosis quite rarely that is a serious complication. However this complication is observed usually during the first 10 days of treatment, the presented case, as a result of inappropriate drug withdrawal and restarting, has emerged after two years from the start of treatment as late onset. After stopping the warfarin therapy , the patient was treated with oral acetylsalicylic acid and skin necrosis regressed within days without recurrence. In the treatment of this complication, parenterally and the new oral anticoagulant agents are the other treatment options.

Tobacco is the leading cause of preventable premature death and disabilities in the world. Current cessation medications include nicotine replacement therapy (NRT), varenicline, and bupropion. Bupropion is used for smoking cessation therapy as well as depression treatment. Bupropion HCL is an antidepresant that acts as a norepinephrine and dopamine reuptake inhibitor and has a favorable side-effect profile. Many drugs may cause skin reactions. Dermatologic adverse effects have increased because use of antidepressant drugs all over the world. The most common side-effects of Bupropion HCL include insomnia, constipation, headache and dry mouth. Unlike these side-effects, we present a case of serum sickness-like reaction due to sustained-release bupropion SR during smoking cessation therapy in this case report.